MCS performs synthesis of specific compounds requested by clustomers. The synthetic route can be supplied by the client or designed and set up in the group.
Compounds are delivered suitably labeled and with an analytical data sheet specifying the characterization and purity of the product (depending on the specifications required by the customer).
MCS has the equipment and expertise for the design of new routes of synthesis with industrial applicability. In these cases, the feasibility of patenting the results is taken into account.
The group not only develops the synthesis, but also provides the analytical method for the characterization of the active ingredient. It also performs the synthesis and characterization of impurities from the main route optimized.
Medicinal Chemistry projects and consulting
MCS has experience in the management and execution of projects of Medicinal Chemistry. The group offers both consultancy in project management as medicinal chemistry design and synthesis of new structures characterization (NMR, HPLC-MS).
Analytical support to organic synthesis and analytical methods development
Accurate chemical analyses are crucial for the successful development of R+D projects and for the correct characterization of products.
Our skilled analysts and instruments allow an efficient development of analytical methods as a part of our projects as well as specific and external uses in case a personalized support is not required.
The available analytical techniques include: HPLC (analytical and preparative scale); HPLC-MS/MS; GC and GC-MS; HRMS. We can provide you both with a large assortment of HPLC columns (direct/reverse phase, ionic exchange, preparative, chiral and UPLC columns) and detectors (ELSD, UV, fluorescence, PDA and MS/MS detectors).
– Quality control of compounds. MCS has the necessary equipment to perform quality control of libraries of compounds by HPLC-MS.
– Isolation and purification of samples. MCS has a wide range of equipment for sample purification (HPLC, HPLC-prep, Isolera-Biotage) with a wide range of detectors (UV, PDA, ELSD, MS) and high number of columns some of them unusual (amides, amines, chiral columns etc).
– Chemical characterization. MCS can carry out the determination of specific properties of compounds or samples in solution such as moisture of a sample, polarimetry, melting points, etc.