Functional hybrid (bio)materials

Case Studies

Overview
Solid surfaces are in general solid inorganic matter and per se not suitable for immobilizing biomolecules such as proteins. In order to construct robust and reliable biosensors it is important to construct hybrid (bio)materials responding to particular demands such as 1. biocompatibility; 2. homogeneity; 3. stability; 4. specificity; and 5. functionalization. However due to the difference in nature between the two components of these new materials, it is necessary to develop appropriate chemical modification approaches to accomplish the above mentioned requirements. Thus, at each development preventing non-specific adsorption is crucial . On the other hand, procedures to provide biocompatible environments may contribute to guarantee functionality of the biomolecules. Site-specfic immobilization is also sometimes required in addition to ensure availability and functionality of the active site of the biomolecule.

Features

Nanogold Probe Enhanced Surface Plasmon Resonance Immunosensor for Improved Detection of Antibiotic Residues



Citation: Fernández, F.; Sánchez-Baeza, F.; Marco, M. P.,  Biosensors and Bioelectronics 2012, 34 (1), 151-158. URL

 

 
Funding
DETECTA (AGL2008-05578-C05-01); OligoCODES (MAT2011-29335-C03-01)
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