{"id":11599,"date":"2026-06-02T16:53:01","date_gmt":"2026-06-02T14:53:01","guid":{"rendered":"https:\/\/www.iqac.csic.es\/personal\/jordi-bujons-vilas\/"},"modified":"2026-06-02T16:53:01","modified_gmt":"2026-06-02T14:53:01","slug":"jordi-bujons-vilas","status":"publish","type":"personal","link":"https:\/\/www.iqac.csic.es\/ca\/personal\/jordi-bujons-vilas\/","title":{"rendered":"Jordi Bujons Vilas"},"content":{"rendered":"<p>Jordi Bujons es va doctorar en Qu\u00edmica Org\u00e0nica per la Universitat de Barcelona el 1994. Posteriorment es va traslladar a la Universitat de British Columbia (Vancouver, Canad\u00e0), on va fer una estada postdoctoral de tres anys al grup del Prof. A. G. Mauk, treballant en la generaci\u00f3 i caracteritzaci\u00f3 de mutants de l\u2019enzim citocrom c peroxidasa. <\/p>\n<p>El 1998 va tornar a l\u2019Institut de Qu\u00edmica Avan\u00e7ada de Catalunya, on es va consolidar com a Cient\u00edfic Titular del CSIC el 2001, incorporant-se posteriorment al grup de Biotransformacions i Compostos Bioactius (2006).<\/p>\n<p>La seva recerca se centra en el disseny computacional i l\u2019estudi mecan\u00edstic d\u2019enzims com a biocatalitzadors en s\u00edntesi org\u00e0nica, amb un \u00e8mfasi especial en la formaci\u00f3 estereoselectiva d\u2019enlla\u00e7os C\u2013X. Aquest treball ha perm\u00e8s l\u2019optimitzaci\u00f3 racional dels centres actius de diferents enzims, especialment aldolases, amb l\u2019objectiu d\u2019ampliar l\u2019abast de substrats, aix\u00ed com millorar l\u2019efici\u00e8ncia catal\u00edtica i l\u2019estereoselectivitat. <\/p>\n<p>Gr\u00e0cies a la seva experi\u00e8ncia en modelatge molecular, tamb\u00e9 ha contribu\u00eft a una \u00e0mplia varietat de projectes en qu\u00edmica biol\u00f2gica i medicinal, que inclouen el disseny de nous reguladors de l\u2019apoptosi, l\u2019estudi de moduladors del receptor GABAA_AA, el modelatge de sistemes supramoleculars i el desenvolupament de mol\u00e8cules PROTAC dirigides a prote\u00efnes d\u2019inter\u00e8s.<\/p>\n","protected":false},"featured_media":11600,"parent":0,"template":"","meta":{"_acf_changed":false},"departamento":[160],"grupo-de-investigacion":[243],"plataforma-tecnologica":[],"servicio":[],"tipo-de-personal":[229,230],"class_list":["post-11599","personal","type-personal","status-publish","has-post-thumbnail","hentry","departamento-quimica-biologica","grupo-de-investigacion-biotransformacio-i-molecules-bioactives-btbm","tipo-de-personal-personal-dinvestigacio-cientifica","tipo-de-personal-personal-investigador-consolidat","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Jordi Bujons Vilas | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iqac.csic.es\/personal\/jordi-bujons-vilas\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jordi Bujons Vilas | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC\" \/>\n<meta property=\"og:description\" content=\"Jordi Bujons es va doctorar en Qu\u00edmica Org\u00e0nica per la Universitat de Barcelona el 1994. 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