{"id":11158,"date":"2026-07-06T13:25:00","date_gmt":"2026-07-06T11:25:00","guid":{"rendered":"https:\/\/www.iqac.csic.es\/proyecto\/nanobombolles-induides-per-laser-a-partir-de-nanobots-impulsats-per-enzims-per-a-la-immunoterapia-del-cancer-de-bufeta\/"},"modified":"2026-09-02T12:12:34","modified_gmt":"2026-09-02T10:12:34","slug":"nanobombolles-induides-per-laser-a-partir-de-nanobots-impulsats-per-enzims-per-a-la-immunoterapia-del-cancer-de-bufeta","status":"publish","type":"proyecto","link":"https:\/\/www.iqac.csic.es\/ca\/projecte\/nanobombolles-induides-per-laser-a-partir-de-nanobots-impulsats-per-enzims-per-a-la-immunoterapia-del-cancer-de-bufeta\/","title":{"rendered":"Nanobombolles indu\u00efdes per l\u00e0ser a partir de nanobots impulsats per enzims per a la immunoter\u00e0pia del c\u00e0ncer de bufeta"},"content":{"rendered":"<p>BubblyBots4BC t\u00e9 com a objectiu desenvolupar una nova immunoter\u00e0pia per al c\u00e0ncer de bufeta utilitzant nanobots d\u2019\u00f2xid de ferro impulsats per ureasa combinats amb irradiaci\u00f3 l\u00e0ser polsada. Despr\u00e9s de l\u2019administraci\u00f3 intravesical, els nanobots estan dissenyats per autopropulsar-se, distribuir-se dins de la bufeta i acumular-se preferentment al teixit tumoral. En activar-se amb l\u00e0ser, generen nanobombolles de vapor que danyen mec\u00e0nicament les c\u00e8l\u00b7lules canceroses i indueixen mort cel\u00b7lular immunog\u00e8nica, afavorint l\u2019alliberament de senyals de perill i l\u2019activaci\u00f3 de c\u00e8l\u00b7lules dendr\u00edtiques. El projecte optimitzar\u00e0 la s\u00edntesi, el moviment, les condicions d\u2019irradiaci\u00f3, l\u2019activaci\u00f3 immunit\u00e0ria, l\u2019acumulaci\u00f3 tumoral i l\u2019efic\u00e0cia terap\u00e8utica en models de c\u00e0ncer de bufeta.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BubblyBots4BC desenvolupa una nova immunoter\u00e0pia contra el c\u00e0ncer de bufeta basada en nanobots d\u2019\u00f2xid de ferro impulsats per enzims, capa\u00e7os d\u2019acumular-se al teixit tumoral i generar nanobombolles de vapor indu\u00efdes per l\u00e0ser. Aquestes nanobombolles busquen induir mort cel\u00b7lular immunog\u00e8nica i promoure una vacunaci\u00f3 in situ que estimuli respostes immunit\u00e0ries antitumorals. <\/p>\n","protected":false},"featured_media":12584,"parent":0,"template":"","meta":{"_acf_changed":false},"tags":[170,179],"enfermedad":[167],"framework":[131],"linea-de-investigacion":[184,168],"class_list":["post-11158","proyecto","type-proyecto","status-publish","has-post-thumbnail","hentry","tag-descobriment-de-farmacs","tag-nanobiotecnologia","enfermedad-cancer","framework-plan-estatal-peicti","linea-de-investigacion-comprendre","linea-de-investigacion-tractar","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nanobombolles indu\u00efdes per l\u00e0ser a partir de nanobots impulsats per enzims per a la immunoter\u00e0pia del c\u00e0ncer de bufeta | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iqac.csic.es\/ca\/projecte\/nanobombolles-induides-per-laser-a-partir-de-nanobots-impulsats-per-enzims-per-a-la-immunoterapia-del-cancer-de-bufeta\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nanobombolles indu\u00efdes per l\u00e0ser a partir de nanobots impulsats per enzims per a la immunoter\u00e0pia del c\u00e0ncer de bufeta | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC\" \/>\n<meta property=\"og:description\" content=\"BubblyBots4BC desenvolupa una nova immunoter\u00e0pia contra el c\u00e0ncer de bufeta basada en nanobots d\u2019\u00f2xid de ferro impulsats per enzims, capa\u00e7os d\u2019acumular-se al teixit tumoral i generar nanobombolles de vapor indu\u00efdes per l\u00e0ser. 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