{"id":11164,"date":"2026-07-06T13:50:36","date_gmt":"2026-07-06T11:50:36","guid":{"rendered":"https:\/\/www.iqac.csic.es\/proyecto\/desxifrant-el-paper-dels-gpcr-intracellulars-en-cellules-cardiaques-mitjancant-estrategies-fotofarmacologiques\/"},"modified":"2026-07-06T13:50:36","modified_gmt":"2026-07-06T11:50:36","slug":"desxifrant-el-paper-dels-gpcr-intracellulars-en-cellules-cardiaques-mitjancant-estrategies-fotofarmacologiques","status":"publish","type":"proyecto","link":"https:\/\/www.iqac.csic.es\/ca\/projecte\/desxifrant-el-paper-dels-gpcr-intracellulars-en-cellules-cardiaques-mitjancant-estrategies-fotofarmacologiques\/","title":{"rendered":"Desxifrant el paper dels GPCR intracel\u00b7lulars en c\u00e8l\u00b7lules card\u00edaques mitjan\u00e7ant estrat\u00e8gies fotofarmacol\u00f2giques"},"content":{"rendered":"<p>Les c\u00e8l\u00b7lules s&#8217;adapten cont\u00ednuament al seu entorn gr\u00e0cies a complexos sistemes de comunicaci\u00f3 interna. Al cor, determinats receptors s\u00f3n essencials per mantenir una activitat equilibrada i, quan fallen, poden apar\u00e8ixer malalties cardiovasculars. No obstant aix\u00f2, encara no es t\u00e9 un coneixement complet de com la seva localitzaci\u00f3 cel\u00b7lular influeix en aquests processos. En el projecte CardioLight, abordem aquesta q\u00fcesti\u00f3 desenvolupant mol\u00e8cules innovadores que es poden controlar amb llum, permetent activar o desactivar l&#8217;activitat cel\u00b7lular amb gran precisi\u00f3. Aquesta estrat\u00e8gia obre la possibilitat de modular la funci\u00f3 card\u00edaca de manera selectiva i reversible. A mesura que puguem aportar una nova comprensi\u00f3 d&#8217;aquests mecanismes en sistemes vius, establirem les bases per a ter\u00e0pies m\u00e9s segures i eficaces.     <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Proposem una estrat\u00e8gia innovadora basada en la fotofarmacologia per abordar diverses necessitats terap\u00e8utiques, incloses les malalties cardiovasculars. Aquesta aproximaci\u00f3 permetria regular l&#8217;activitat del cor de forma precisa i reversible, amb potencial per millorar temporalment la seva funci\u00f3 i ajudar a estabilitzar alteracions del ritme en situacions cr\u00edtiques. <\/p>\n","protected":false},"featured_media":11166,"parent":0,"template":"","meta":{"_acf_changed":false},"tags":[170,169],"enfermedad":[188],"framework":[131],"linea-de-investigacion":[184,168],"class_list":["post-11164","proyecto","type-proyecto","status-publish","has-post-thumbnail","hentry","tag-descobriment-de-farmacs","tag-quimica-medica","enfermedad-cardiovascular","framework-plan-estatal-peicti","linea-de-investigacion-comprendre","linea-de-investigacion-tractar","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Desxifrant el paper dels GPCR intracel\u00b7lulars en c\u00e8l\u00b7lules card\u00edaques mitjan\u00e7ant estrat\u00e8gies fotofarmacol\u00f2giques | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iqac.csic.es\/proyecto\/descifrando-el-papel-de-los-gpcr-intracelulares-en-celulas-cardiacas-mediante-estrategias-fotofarmacologicas\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Desxifrant el paper dels GPCR intracel\u00b7lulars en c\u00e8l\u00b7lules card\u00edaques mitjan\u00e7ant estrat\u00e8gies fotofarmacol\u00f2giques | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC\" \/>\n<meta property=\"og:description\" content=\"Proposem una estrat\u00e8gia innovadora basada en la fotofarmacologia per abordar diverses necessitats terap\u00e8utiques, incloses les malalties cardiovasculars. 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