Juan Fraire

Ramón y Cajal

IQAC

Department

Surfactants and Nanobiotechnology

Research group

Nanomedicine for Therapeutic Applications (NM4T)

Contact

Email

juan.fraire@iqac.csic.es

Extension

437924

Profiles

ORCID

0000-0002-4887-2161

Juan Fraire

Ramón y Cajal

Juan Fraire obtained his PhD in Chemistry from the University of Córdoba (Argentina) in 2016. After his doctorate, he joined the Laboratory of General Biochemistry and Physical Pharmacy at Ghent University (Belgium) as a postdoctoral researcher, where he worked on photoporation as an advanced drug delivery technique for nucleic acid-based therapies and cell transfection. He has received prestigious fellowships, including those from CONICET (Argentina), Fulbright (Boston University, USA), FWO (Ghent University, Belgium), and Beatriu de Pinós – Marie-Curie COFUND (IBEC, Spain). His initial contributions have been recognized with the Ocean Optics Young Investigator Award and the Sabato Institute Award. In 2021, he joined the Smart Nano-Bio-Devices group at the Institute for Bioengineering of Catalonia (IBEC, Spain), and was promoted to senior researcher in 2023.

Juan is a Ramón y Cajal Principal Investigator at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) within the Nanomedicine for Therapeutic Applications (NM4T) group, where he leads the Gene and Light Nanotherapies Lab (GLNT). His research interests include the rational design of nanocarriers for nucleic acid delivery, leveraging light-activated effects for intracellular delivery and immunogenic activation, and the development of stimulus-responsive nanosystems.

Learn more at frairelab.com

BubblyBots4BC develops a novel bladder cancer immunotherapy based on enzyme-powered iron oxide nanobots capable of accumulating in tumor tissue and generating laser-induced vapor nanobubbles. These nanobubbles seek to induce immunogenic cell death and promote in situ vaccination that stimulates antitumor immune responses.