{"id":11056,"date":"2026-07-07T13:14:39","date_gmt":"2026-07-07T11:14:39","guid":{"rendered":"https:\/\/www.iqac.csic.es\/proyecto\/bacterial-quorum-sensing-connecting-diagnostics-microbiota-and-therapy\/"},"modified":"2026-07-07T13:14:39","modified_gmt":"2026-07-07T11:14:39","slug":"bacterial-quorum-sensing-connecting-diagnostics-microbiota-and-therapy","status":"publish","type":"proyecto","link":"https:\/\/www.iqac.csic.es\/en\/project\/bacterial-quorum-sensing-connecting-diagnostics-microbiota-and-therapy\/","title":{"rendered":"Bacterial Quorum Sensing: Connecting Diagnostics, Microbiota, and Therapy"},"content":{"rendered":"<p>UNLOCKING-QS addresses one of the main threats to health: antimicrobial resistance (AMR) linked to infectious diseases.<\/p>\n<p>The lack of effective diagnostics is a key factor driving AMR, as broad-spectrum antibiotics are often prescribed without identifying the pathogen. This project proposes a new generation of innovative diagnostic and therapeutic strategies targeting bacterial <em>quorum sensing<\/em> (QS), a sophisticated communication system that uses chemical signals (QSsm) to maintain community life and synchronize behavior to develop pathogenesis. <\/p>\n<p>QSsm could act as infection biomarkers, and blocking them would allow for the development of innovative therapeutic approaches. These hypotheses have been partially demonstrated in previous research by the group, and UNLOCKING-QS seeks to consolidate these results by measuring the QS footprint (QSome) in prospective biological samples, as well as exploring the therapeutic potential of antibodies targeting QSsm as QS disruptors. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>UNLOCKING-QS aims to develop diagnostic and therapeutic strategies for bacterial infectious diseases targeting quorum sensing. These innovative approaches are expected to contribute to curbing antimicrobial resistance and improving patient management for better care. <\/p>\n","protected":false},"featured_media":11057,"parent":0,"template":"","meta":{"_acf_changed":false},"tags":[182],"enfermedad":[185],"framework":[131],"linea-de-investigacion":[181,163],"class_list":["post-11056","proyecto","type-proyecto","status-publish","has-post-thumbnail","hentry","tag-nanobiotechnology","enfermedad-infectious","framework-plan-estatal-peicti","linea-de-investigacion-detect","linea-de-investigacion-understand","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bacterial Quorum Sensing: Connecting Diagnostics, Microbiota, and Therapy | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iqac.csic.es\/en\/project\/bacterial-quorum-sensing-connecting-diagnostics-microbiota-and-therapy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bacterial Quorum Sensing: Connecting Diagnostics, Microbiota, and Therapy | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC\" \/>\n<meta property=\"og:description\" content=\"UNLOCKING-QS aims to develop diagnostic and therapeutic strategies for bacterial infectious diseases targeting quorum sensing. 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