{"id":11148,"date":"2026-07-06T14:37:00","date_gmt":"2026-07-06T12:37:00","guid":{"rendered":"https:\/\/www.iqac.csic.es\/proyecto\/light-activated-non-opioid-drugs-for-pain-treatment-without-side-effects\/"},"modified":"2026-07-06T14:37:00","modified_gmt":"2026-07-06T12:37:00","slug":"light-activated-non-opioid-drugs-for-pain-treatment-without-side-effects","status":"publish","type":"proyecto","link":"https:\/\/www.iqac.csic.es\/en\/project\/light-activated-non-opioid-drugs-for-pain-treatment-without-side-effects\/","title":{"rendered":"Light-activated non-opioid drugs for pain treatment without side effects"},"content":{"rendered":"<p>Current analgesic treatments have significant limitations, as they very often affect the entire organism and can generate adverse effects due to systemic drug exposure. In the Druglight4Pain consortium, we propose an innovative strategy based on a new non-opioid therapeutic target that can be utilized through light-sensitive compounds, activated only locally and at specific times. This allows for localized and reversible pain control, reducing systemic drug exposure and improving safety. The project combines advances in chemistry and biomedicine to develop new, safer, and more effective therapeutic solutions, contributing to improving patients&#8217; quality of life.   <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Current treatments for chronic and acute pain, such as opioids, act systemically and often cause severe side effects. Within the framework of this project, we are exploring the use of light-activatable drugs to achieve more precise, localized, and safer pain control. <\/p>\n","protected":false},"featured_media":11149,"parent":0,"template":"","meta":{"_acf_changed":false},"tags":[174,173],"enfermedad":[180],"framework":[133],"linea-de-investigacion":[172,163],"class_list":["post-11148","proyecto","type-proyecto","status-publish","has-post-thumbnail","hentry","tag-drug-discovery","tag-medicinal-chemistry","enfermedad-neurodegenerative","framework-fundacio-la-caixa","linea-de-investigacion-treat","linea-de-investigacion-understand","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Light-activated non-opioid drugs for pain treatment without side effects | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iqac.csic.es\/en\/project\/light-activated-non-opioid-drugs-for-pain-treatment-without-side-effects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Light-activated non-opioid drugs for pain treatment without side effects | IQAC - Institut de Qu\u00edmica Avan\u00e7ada de Catalunya - CSIC\" \/>\n<meta property=\"og:description\" content=\"Current treatments for chronic and acute pain, such as opioids, act systemically and often cause severe side effects. 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