Innovation and Transfer

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Assets / R+D Contracts

Patents

Immunoassay for detecting fluoroquinolone-type antibiotic residues in food. [Licensed]

fluoroquinolones to determine their residues in food. The immunoassay is rapid and efficient, with detection limits of 0.025-6 ppb depending on the fluoroquinolone, matrix, and animal species, and detects fluoroquinolones undetectable by other methods.

✦ Filing year: 2010

✦ Industrial property: Licensed patent

✦ TRL: 9

Multiplexed Liquid System in Biosensor Microcells [Licensed]

a fluid using biosensors introduced into a plurality of microchambers, in which said fluid is supplied, with identical flow, in independently controlled functional periods. This technology can be applied to the in situ quantification of contaminants and other analytes, especially for environmental monitoring in marine or river waters.

✦ Filing year: 2017

✦ Industrial property: Licensed patent

✦ TRL: 5

Bicosomes: bicelles encapsulated in liposomes and their application in diluted systems. [Licensed]

in such a way that the morphology of the bicelles is preserved in diluted environments. Bicosomes allow for the encapsulation and delivery of drugs, dyes, or pigments, acting as vehicles for substances of cosmetic, dermatological, and pharmaceutical interest in diluted aqueous solutions and as permeability enhancers for biological membranes.

✦ Filing year: 2010

✦ Industrial property: Licensed patent

✦ TRL: 9

Accurate diagnosis of diseases related to cystine accumulation, such as cystinosis and cystinuria

cystine accumulation, such as cystinosis and cystinuria, based on a molecular network that produces a measurable fluorescence signal when certain substances bind to abnormal levels of cysteine or cystine.

✦ Filing year: 2018

✦ Industrial property: Patent granted in EP and filed in the USA (pending)

✦ TRL: 3

Rapid Diagnosis of Infections Caused by Pseudomonas aeruginosa

by Pseudomonas aeruginosa through the detection of the main signaling molecules of the pqs system of Quorum Sensing. The immunoassay is rapid, efficient and highly sensitive, adaptable to point-of-care systems.

✦ Filing year: 2020

✦ Industrial property: Patent applied for in the USA and Europe

✦ TRL: 4

Liposomal lipid formulations to reduce pathogen permeation through the oral mucosa

…corneum, capable of acting as oral mucosa waterproofing agents to prevent the penetration of viruses or biocides through the mucosa.

 

✦ Filing year: 2023

✦ Industrial property: International PCT application filed

✦ TRL: 3-4

New type of protacs directly targeting the proteasome for cancer treatment

aimed at the degradation of ceramide transfer protein (CERT-1) by the proteasome, independently of E3, for use in the treatment of breast cancer.

✦ Filing year: 2024

✦ Industrial property: Priority European patent application

✦ TRL: 3

Mactide-V, an effective peptide–drug conjugate for the treatment of triple-negative breast cancer

Modulation of the phenotype of tumour-associated CD206+ macrophages by means of a new peptide–drug conjugate (PDC) capable of slowing tumour progression and suppressing lung metastasis.

 

✦ Filing year: 2024

✦ Industrial property: Priority European patent application

✦ TRL: 4

Compounds for Local and Temporally Restricted Activation of the Vitamin D Receptor

for the activation of the Vitamin D Receptor (VDR), which would prevent the occurrence of side effects, with application for the treatment of diseases involving an alteration of VDR function.

 

✦ Filing year: 2025

✦ Industrial property: Priority European patent application

✦ TRL: 3

Light-regulated beta-blocker compounds for the treatment of eye diseases

for localized and temporally restricted activation of beta-adrenergic receptors, with application in the treatment of eye diseases such as glaucoma.

✦ Filing year: 2025

✦ Industrial property: Priority European patent application

✦ TRL: 3