Research | Technological Platforms

Peptide Synthesis Unit

The Synthesis of Peptides Unit offers peptide synthesis services in quantities ranging from milligrams to grams, as well as services for their purification and characterization. This unit also has extensive experience in post-peptide synthesis modifications, including conjugation with drugs, polymers, proteins, and fluorescent compounds. This unit is also part of the CIBER-BBN NANBIOSIS ICTS (Unit 3), providing services that are complementary to others offered by this ICTS.

Contact: miriam.royo@iqac.csic.es

Services

  • Peptide synthesis and characterization (scales: 10, 50, and 100 mg; Purity: crude and ≥ 95%)
  • Post-synthesis peptide modification, for example, cyclization via amide bond, disulfide bridge, or C-C (stapled peptides)
  • Conjugation of peptides to drugs, polymers, or proteins
  • Synthesis of special amino acids
  • Synthesis of peptidomimetics

EQUIPMENT

  • Microwave-assisted automated peptide synthesizer
    HPLC-PDA-ELSD:
  • High-performance liquid chromatography (HPLC) system with a photodiode array detector (PDA) and an evaporative light scattering detector (ELSD)
    HPLC-PDA-MS:
  • High-performance liquid chromatography (HPLC) system with a photodiode array detector (PDA), coupled to a mass spectrometer (MS).

Staff

Daniel Pulido Martínez

Tenured Scientist

Miriam Royo

Research Scientist