COLLOIDAL AND INTERFACIAL CHEMISTRY
Group Leader: Carlos Rodríguez
MISSION
To understand and control colloidal phenomena using singular chemical strategies for the design and development of technological applications.
VISION
Consolidate innovation in colloid chemistry as the driving force to solve specific technological and societal challenges
Our group is focused on the molecular self-assembly in soft matter as a vehicle for the bottom-up fabrication of nanomaterials. with minimum use of energy. We are interested in nanostructured systems such as surfactants, polymers, micelles, gels, liquid crystals, foams, microemulsions and nano-emulsions; they can find direct applications or be used as templates, structure directing agents or nanoreactors for the synthesis of nanoparticles, nanocomposites or nanoporous solids. Through state-of-the-art techniques, we intend to understand the fundamentals mechanisms of aggregation, colloidal forces and interfacial interactions and their impact on material domain size, structure, stability and other properties. We aim to use molecular information and physicochemical parameters to predict, control and program hierarchical self-organization at multiple scales and with increasing complexity, for materials with new or improved properties and applications.
Web of the group: http://www.iqac.csic.es/qci/
Our research is focused in the following lines:
- Development of tailor-made formulations for novel applications based on the self-assembly of surfactant molecules, polymers and other colloidal systems.
- Self-assemblies and colloidal dispersions as templates or structure-directing agents in the preparation of advanced functional materials.
- Design and synthesis of molecular delivery systems towards applications in therapy.
Scientific staff
Carlos Federico Rodríguez
Scientific Researcher
carlos.rodriguez@iqac.csic.es
Lab people
Gabriela Calderó
Visiting lecturer UB
gabriela.caldero@iqac.csic.es
Santiago Grijalvo
CIBER Researcher
santiago.grijalvo@iqac.csic.es
Adrià Pérez Calm
Predoctoral Rechearcher
adria.perez@iqac.csic.es
José Antonio Durán González
Technician
joseantonio.duran@iqac.csic.es
Víctor Espinosa
Undergraduate student, UB
victor.espinosa@iqac.csic.es
Mateo Pava
Internship student, ICESI University, Colombia
mateo.pava@iqac.csic.es
- Effects of a nanoemulsion with Copaifera officinalis oleoresin against monogenean parasites of Colossoma macropomum: A Neotropical Serrasalmidae-
Valentim, D.S.S., Duarte, J.L., Oliveira, A.E.M.F.M., Cruz, R.A.S., Carvalho, J.C.T., Solans, C., Fernandes, C.P., Tavares-Dias, M.
J Fish Diseases (2018), 41 (7), pp. 1041-1048.
- Hyaluronan based materials with catanionic sugar-derivedsurfactants as drug delivery systems.-
Roig, M. Blanzat, C. Solans, J. Esquena, M.J. García-Celma
Colloids Surf B: Biointerfaces 2018, 164, 218–223.
- Effect of surface chemistry and associated protein corona on the long-term biodegradation of iron oxide nanoparticles in vivo.-
Stepien, M. Moros, M. Perez-Hernandez, M. Monge, L .Gutiérrez, R.M.M. Fratila, M. Las Heras, S. Menao Guillen, J.J. Puente Lanzarote, C. Solans, J. Pardo, J.M. De La Fuente
ACS Appl Mater Interfaces 2018, 10, 4548−4560.
- Rivas Novel synthetic routes of large-pore magnetic mesoporous nanocomposites (SBA-15/Fe3O4) as potential multifunctional theranostic nanodevices.-
Z.Vargas-Osorio, M.A. Gonzáles-Gómez, Y. Piñeiro, C. Vázquez-Vázquez, C. Rodríguez-Abreu, M.A. López-Quintela, J.
J Mater Chem. B, 2017, 5, 9395-9404.
- Design of parenteral MNP-loaded PLGA nanoparticles by a low-energy emulsification approach as theragnostic platforms for intravenous or intratumoral administration.-
Calderó, C. Fornaguera, L. Zadoina, A. Dols-Perez, C. Solans.
Colloids Surf B: Biointerfaces 2017, 160 ,535–542.
- Adsorption of Marine Phycotoxin Okadaic Acid on a Covalent Organic Framework.-
M. Salonen, S. R. Pinela, S. P.S. Fernandes, J. Loucano, E. Carbo-Argibay, M. P. Sarria, C. Rodrıguez-Abreu, J. Peixoto, B. Espiña.
J Chromatogr A. 2017, 2017,1525, 17–22.
- Emulsion-based Gels with Thermally Switchable Transparency.-
K.Aramaki, K.Masuda, R.Horie, C.Rodríguez-Abreu.
Colloids and Surfaces A: Physicochem Engineer Aspects 2017, 533, 302-307.
- Green synthesis of silver nanoparticles in oil-in-water microemulsion and nano-emulsion using geranium leaf aqueous extract as a reducing agent.-
Rivera-Rangel, R.D., González-Muñoz, M.P., Avila-Rodriguez, M., Razo-Lazcano, T.A., Solans, C.
Colloids Surf A: Physicochem Engin Aspects 2018, 536, 60-67.
- Influence of crosslinked alginate on drug release from highly concentrated emulsions.-
Bonilla, P., Arias, E.M., Solans, C., García-Celma, M.J.
Colloids Surfs A: PhysicocheEngin Aspects 2018, 536, pp. 148-155.
- A colloidally stable water dispersion of Ni nanowires as efficient T2-MRI contrast agent.-
M.Banobre Lopez, C.Bran, C. Rodriguez-Abreu, J. Gallo, M.Vazquez, J. Rivas.
J Mater Chem B, 2017, 5, 3338--3347.
- Versatile Methodology to Encapsulate Gold Nanoparticles in PLGA Nanoparticles Obtained by Nano-Emulsion Templating.-
Fornaguera, N. Feiner-Gracia, A. Dols-Perez, M. J. García-Celma, C. Solans.
Pharmaceutical Research 2017, 34, 1093-1103
- PLGA nanoparticles from nano-emulsion templating as imaging agents: Versatile technology to obtain nanoparticles loaded with fluorescent dyes.-
Fornaguera, N. Feiner-Gracia., G. Calderó, M.J.Garcia-Celma, C. Solans
Colloids Surf B: Biointerfaces 2016, 147, 201 - 209.
- From Chromonic Self-Assembly to Hollow Carbon Nanofibers: Efficient Materials in Supercapacitor and Vapor-Sensing Applications.-
J.R. Magana, Y.V. Kolen'ko, F.L. Deepak, C. Solans, R.G. Shrestha, J.P. Hill, K. Ariga, L.K. Shrestha, C. Rodriguez-Abreu .
ACS Appl Mater Interfaces 2016, 8, 31231–31238.
- Self-Assembly and Formation of Chromonic Liquid Crystals from the Dyes Quinaldine Red Acetate and Pyronin Y.-
R. Magana, M. Homs, C. Solans, M. Obiols-Rabasa, L. M. Salonen, C. Rodríguez-Abreu.
J Phys Chem B 2016, 120, 250–258.
- PLGA nanoparticles prepared by nano-emulsion templating using low-energy methods as efficient nanocarriers for drug delivery across the blood–brain barrier.-
Fornaguera, A. Dols-Perez, G. Calderó, M.J. García-Celma, J. Camarasa, C. Solans.
J Controlled Release. 2015, 211, 134-143.
- Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies.-
Fornaguera, G.Calderó, M.Mitjans, M. P. Vinardell, C. Solans, C. Vauthier.
Nanoscale 2015, 7, 6045-6058.
- Chromonic self-assemblies in a series of dialkyl-thiacarbocyanine dyes and generalization of a facile route for the synthesis of fluorescent nanostructured silica fibers-
Magana, J.R., Solans, C., Salonen, L.M., Carbó-Argibay, E., Gallo, J., Tiddy, G.J.T., Rodríguez-Abreu, C.
J Taiwan Inst Chem Engin, 92, 134-142, 2018.
- Editorial for Special issue on Formula VIII-
Durand, A., Faers, M., Rodríguez-Abreu, C.
Colloids Surf A: Physicochem Engin Aspects, 2018, 536, pp. 1-2.
- NLCs as a potential carrier system for transdermal delivery of forskolin-
Lason, E., Sikora, E., Miastkowska, M., Escribano, E., Garcia-Celma, M.J., Solans, C., Llinas, M., Ogonowski, J.
Acta Biochimica Polonica, 65 (3), pp. 437-442. 2018
- Low-energy nano-emulsification approach as a simple strategy to prepare positively charged ethylcellulose nanoparticles-
Leitner, S., Solans, C., García-Celma, M.J., Calderó, G.
Carbohydrate Polymers, 205, pp. 117-124. 2019
- Analytical Methods to Characterize and Purify Polymeric Nanoparticles-
Fornaguera, C., Solans, C.
International Journal of Polymer Science, 2018, art. no. 6387826, 2018
- Electrical Impedance Spectroscopy Microflow Cytometer for Cell Viability Tests-
González-Murillo, J.J., Monge-Azemar, M., Bartoli, J., Flores, A., Moreno, M., García-Celma, M., Romano-Rodríguez, A., Svendsen, W., Samitier, J., Rodríguez-Trujillo, R.
Proceedings of the 2018 12th Spanish Conference on Electron Devices, CDE 2018, art. no. 8597037, 2018
- Formation of Nanoemulsion Containing Ibuprofen by PIC Method for Topical Delivery-
Salim, N., Jose García-Celma, M., Escribano, E., Nolla, J., Llinàs, M., Basri, M., Solans, C., Esquena, J., Tadros, T.F.
Materials Today: Proceedings, 5, pp. S172-S179. 2018
- Simultaneous extraction and obtention of a novel nano-dispersion from Mikania glomerata Spreng: Monitoring coumarin content and increasing the biological and industrial potential of a classical cultivated herb-
Santana, E.A., Rodrigues, R.F., de Almeida, F.B., Oliveira, A.E.M.D.F.M., Cruz, R.A.S., França, H.S., Batitucci, M.D.C.P., Dutra, J.C.V., da Silva Ferreira, P., Amado, J.R.R., Carvalho, J.C.T., Kelmann, R.G., Solans, C., Fernandes, C.P.
Industrial Crops and Products, 135, pp. 49-56.2019
- Food-grade Pickering stabilizers obtained from a protein-rich lupin cultivar (AluProt-CGNA®): Chemical characterization and emulsifying properties-
Burgos-Díaz, C., Wandersleben, T., Olivos, M., Lichtin, N., Bustamante, M., Solans, C.
Food Hydrocolloids, 87, pp. 847-857. 2019
- Formulating stable hexosome dispersions with a technical grade diglycerol-based surfactant-
Magana, J.R., Homs, M., Esquena, J., Freilich, I., Kesselman, E., Danino, D., Rodríguez-Abreu, C., Solans, C.
Journal of Colloid and Interface Science, 550, pp. 73-80. 2019
- Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates-
Calderó, G., Leitner, S., García-Celma, M.J., Solans, C.
Carbohydrate Polymers, 225, art. no. 115201, 2019
- 32nd Conference of the European Colloid and Interface Society, 2–7 September 2018 in Ljubljana, Slovenia-
Bešter-Rogač, M., Kroflič, A., Rodríguez-Abreu, C.
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 580, art. no. 123849,2019
- Cubic liquid crystalline structures in diluted, concentrated and highly concentrated emulsions for topical application: Influence on drug release and human skin permeation-
Arias, E.M., Guiró, P., Rodriguez-Abreu, C., Solans, C., Escribano-Ferrer, E., García-Celma, M.J.
International Journal of Pharmaceutics, 569, art. no. 118531, 2019
- Template-directed self-organization of colloidal PbTe nanocrystals into pillars, conformal coatings, and self-supported membranes-
Piotrowski, M., Borme, J., Carbó-Argibay, E., Sharma, D., Nicoara, N., Sadewasser, S., Petrovykh, D.Y., Rodríguez-Abreu, C., Kolen'Ko, Y.V.
Nanoscale Advances, 1 (8), pp. 3049-3055. 2019
- PLGA cationic nanoparticles, obtained from nano-emulsion templating, as potential DNA vaccines-
Soler Besumbes, E., Fornaguera, C., Monge, M., García-Celma, M.J., Carrión, J., Solans, C., Dols-Perez, A.
European Polymer Journal, 120, art. no. 109229, 2019, .
- Simple Method for Rheological Determination of Surfactant Layer Thickness, Adsorbed on Soft Rubber Particles-
Singh, M., Tadros, T.F., Solans, C., Booten, K., Levecke, B., Esquena, J.
Langmuir, 2019
- Biomedical perfluorohexane-loaded nanocapsules prepared by low-energy emulsification and selective solvent diffusion-
Calderó, G., Rodríguez-Abreu, C., González, A., Monge, M., García-Celma, M.J., Solans, C.
Materials Science and Engineering C, 111, art. no. 110838, 2020
- Key features of nano-emulsion formation by the phase inversion temperature method-
Feng, J., Esquena, J., Rodriguez-Abreu, C., Solans, C.
Journal of Dispersion Science and Technology, .2020
- A Concise Review on Nano‐emulsion Formation by the Phase Inversion Composition (PIC) Method-
Feng, J., Rodríguez-Abreu, C., Esquena, J., Solans, C.
Journal of Surfactants and Detergents, 2020
- Short and ultrashort antimicrobial peptides anchored onto soft commercial contact lenses inhibit bacterial adhesion-
Salvagni, E., García, C., Manresa, À., Müller-Sánchez, C., Reina, M., Rodríguez-Abreu, C., García-Celma, M.J., Esquena, J.
Colloids and Surfaces B: Biointerfaces, 196, art. no. 111283, 2020
- Ultrasound/radiation-responsive emulsions-
Calderó, G., Paradossi, G.
Current Opinion in Colloid and Interface Science, 49, pp. 118-132. 2020
- 1D materials from ionic self-assembly in mixtures containing chromonic liquid crystal mesogens-
Rodríguez-Abreu, C., Kolen'ko, Y.V., Kovnir, K., Sanchez-Dominguez, M., Shrestha, R.G., Bairi, P., Ariga, K., Shrestha, L.K.
Physical Chemistry Chemical Physics, 22 (40), pp. 23276-23285. 2020
- PEGylated perylene bisimides: Chromonic building blocks for the aqueous synthesis of nanostructured silica materials-
Pérez-Calm, A., Esquena, J., Salonen, L.M., Rodríguez-Abreu, C.
Journal of Molecular Liquids, 325, art. no. 114657, 2021.
- Ethylcellulose nanoparticles prepared from nano-emulsion templates as new folate binding haemocompatible platforms-
Leitner, S., Solans, C., García-Celma, M.J., Morral-Ruíz, G., Melgar-Lesmes, P., Calderó, G.
Materials Science and Engineering C, art. no. 111682, 2020
- Preparation of non-toxic nano-emulsions based on a classical and promising Brazilian plant species through a low-energy concept-
Ortiz-Zamora, L., Bezerra, D.C., de Oliveira, H.N.S., Duarte, J.L., Guisado-Bourzac, F., Chil-Núñez, I., da Conceição, E.C., Barroso, A., Mourão, R.H.V., de Faria Mota Oliveira, A.E.M., Cruz, R.A.S., Carvalho, J.C.T., Solans, C., Fernandes, C.P.
Industrial Crops and Products, 158, art. no. 112989, 2020
- Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase-
Alvarez-Dominguez, C., Salcines-Cuevas, D., Teran-Navarro, H., Calderon-Gonzalez, R., Tobes, R., Garcia, I., Grijalvo, S., Paradela, A., Seoane, A., Sangari, F.J., Fresno, M., Calvo-Montes, J., Pérez Del Molino Bernal, I.C., Yañez-Diaz, S.
Frontiers in Cellular and Infection Microbiology, 10, art. no. 573348, . 2020
- Screening of extra virgin olive oil-in-bitter orange juice (O/W) nano-emulsions stabilized with different food-grade surfactants: A model system for natural daily use salad dressing-
Yalçinöz, Ş., Erçelebi, E., Solans, C., Tadros, T.
Italian Journal of Food Science, 32 (4), pp. 873-892. 2020
- Ethylcellulose nanoparticles prepared from nano-emulsion templates as new folate binding haemocompatible platforms-
Leitner, S., Solans, C., García-Celma, M.J., Morral-Ruíz, G., Melgar-Lesmes, P., Calderó, G.
Materials Science and Engineering C, 120, art. no. 111682, 2021
- Mechanochemical Synthesis of TiO2 Nanoparticles and Their Self-organization at Interfaces to Produce Emulsion-Templated Photocatalytic Porous Polymers-
Vílchez, A., Rodriguez-Abreu, C., Esquena, J., Botta, P.M.
Journal of Inorganic and Organometallic Polymers and Materials, 2021
- Graphene-based hybrid materials as promising scaffolds for peripheral nerve regeneration-
Grijalvo, S., Díaz, D.D.
Neurochemistry International, 147 art. no. 105005, 2021
- A nanocellulose-based platform towards targeted chemo-photodynamic/photothermal cancer therapy-
Do, T.T.A., Grijalvo, S., Imae, T., Garcia-Celma, M.J., Rodríguez-Abreu, C.
Carbohydrate Polymers, 270, art. no. 118366, 2021
- Xanthan-Fe3O4Nanoparticle Composite Hydrogels for Non-Invasive Magnetic Resonance Imaging and Magnetically Assisted Drug Delivery-
Ribeiro, M., Boudoukhani, M., Belmonte-Reche, E., Genicio, N., Sillankorva, S., Gallo, J., Rodríguez-Abreu, C., Moulai-Mostefa, N., Bañobre-López, M.
ACS Applied Nano Materials, 4 (8), pp. 7712-7729. 2021
- Deconstruction of technical grade diglycerol isostearate enables the controlled preparation of hexosomes and liposomes-
Magana, J.R., Esquena, J., Solans, C., Rodriguez-Abreu, C.
Journal of Molecular Liquids, 343, art. no. 117594, 2021
- Chromonic Nematic Liquid Crystals in a Room-Temperature Ionic Liquid-
Jose Rodrigo Magana, Adrià Pérez-Calm and Carlos Rodríguez-Abreu
Chem. Commun., 2022
- Rosmarinic Acid-Loaded Polymeric Nanoparticles Prepared by Low-Energy Nano-Emulsion Templating: Formulation, Biophysical Characterization, and In Vitro Studies-
García-Melero, J., López-Mitjavila, J.-J., García-Celma, M.J., Rodriguez-Abreu, C., Grijalvo, S.
Materials, 15 (13), art. no. 4572, 2022
- A post-synthetic modification strategy for the synthesis of pyrene-fused azaacene covalent organic frameworks-
Fernandes, S.P.S., Frey, L., Cid-Seara, K.M., Oliveira, O., Guldris, N., Carbó-Argibay, E., Rodríguez-Abreu, C., Kolen'ko, Y.V., Silva, A.M.S., Medina, D.D., Salonen, .M.
Microporous and Mesoporous Materials, 343, art. no. 112162, 2022
- Ferulic acid-loaded polymeric nanoparticles prepared from nano-emulsion templates facilitate internalisation across the blood-brain barrier in model membranes-
Garcia, L., Palma-Florez, S., Espinosa, V., Soleimani Rokni, F., Lagunas, A., Mir, M., García-Celma, M.J., Samitier, J., Rodríguez-Abreu, C., Grijalvo, S.
Nanoscale, 15 (17), pp. 7929-7944. 2023
- Electrocatalytic Pt-embedded ZIF-8 on nanocellulose-based flexible conductive electrodes for hydrogen evolution reaction-
Krathumkhet, N., Kao, C.-Y., Imae, T., Rodriguez-Abreu, C.
Cellulose, 30 (5), pp. 3185-3200. 2023
- Unravelling the role of individual components in pBAE/polynucleotide polyplexes in the synthesis of tailored carriers for specific applications: on the road to rational formulations-
Navalón-López, M., Dols-Perez, A., Grijalvo, S., Fornaguera, C., Borrós, S.
Nanoscale Advances, 5 (6), pp. 1611-1623. 2023
- Effect of surface functionalization and loading on the mechanical properties of soft polymeric nanoparticles prepared by nano-emulsion templating-
Dols-Perez, A., Fornaguera, C., Feiner-Gracia, N., Grijalvo, S., Solans, C., Gomila, G.
Colloids and Surfaces B: Biointerfaces, 222, art. no. 113019, .
- Polymer nanoparticles from low-energy nanoemulsions for biomedical applications-
Grijalvo, S., Rodriguez-Abreu, C.
Beilstein Journal of Nanotechnology, 14, pp. 339-350.
- Study of nanoemulsions using carvacrol/MCT-(Oleic acid-potassium oleate)/ Tween 80 ®- water system by low energy method-
Santamaría, E., Maestro, A., Vilchez, S., González, C.
Heliyon, 9 (6), 2023
- EHO-85, Novel Amorphous Antioxidant Hydrogel, Containing Olea europaea Leaf Extract—Rheological Properties, and Superiority over a Standard Hydrogel in Accelerating Early Wound Healing: A Randomized Controlled Trial-
Verdú-Soriano, J., de Cristino-Espinar, M., Luna-Morales, S., Dios-Guerra, C., Casado-Díaz, A., Quesada-Gómez, J.M., Dorado, G., Berenguer-Pérez, M., Vílchez, S., Esquena, J., Rodríguez-Mañas, L., Lázaro-Martínez, J.L.
Pharmaceutics, 15 (7), art. no. 1925, 2023.
- AYUDAS PROMOCIÓN EMPLEO JOVEN 2018 (AEI)-
Referencia: PEJ2018-001872-P
Financiador: MINISTERIO DE CIENCIA INNOVACIÓN Y UNIVERSIDADES - AGENCIA ESTATAL DE INVESTIGACIÓN; UNIÓN EUROPEA, FONDO SOCIAL EUROPEO (El FSE invietre en tu futuro).
Beneficiario: JOSÉ ANTONIO DURAN GONZÁLEZ.
Comienzo: 01/12/2019 Final: 30/11/2021
- Mesostructured Materials with Controllable Long-Range Orientational Ordering and Anisotropic Properties-
Jahnke, J.P., Kim, D., Wildemuth, D.J., Nolla, J., Berkow, M.W., Gwak, H., Neyshtadt, S., Segal-Peretz, T., Frey, G.L., Chmelka, B.F.
Advanced Materials, 35 (51), art. no. 2306800, 2023
- AYUDAS PROMOCIÓN EMPLEO JOVEN 2018 (AEI)-
Referencia: PEJ2018-001872-P
Financiador: MINISTERIO DE CIENCIA INNOVACIÓN Y UNIVERSIDADES - AGENCIA ESTATAL DE INVESTIGACIÓN; UNIÓN EUROPEA, FONDO SOCIAL EUROPEO (El FSE invietre en tu futuro).
Beneficiario: JOSÉ ANTONIO DURAN GONZÁLEZ.
Comienzo: 01/12/2019 Final: 30/11/2021
IQAC
Institut de Química Avançada de Catalunya
c/ Jordi Girona 18-26
08034 Barcelona - Spain
Ph: +34 93 400 61 00
Fax: +34 93 204 59 04