Xavier Rovira Algans

Tenured Scientist

IQAC

Department

Biological Chemistry

Research group

Medicinal Chemistry and Synthesis (MCS)

Contact

Email

xavier.rovira@iqac.csic.es

Phone

93 4006171

Extension

437701

Profiles

ORCID

0000-0002-9764-9927

LinkedIn

Xavier Rovira

Xavier Rovira Algans

Tenured Scientist

Xavier Rovira Algans obtained his PhD at the Institute of Neurosciences of the Autonomous University of Barcelona (UAB). He received several competitive grants that enabled him to undertake two predoctoral stays at Cornell University (New York) and at Université Paris Descartes (Paris), as well as a postdoctoral stay of around 5 years at the Institut de Génomique Fonctionnelle (Montpellier). These experiences allowed him to specialise in mathematical and molecular modelling of biological systems, cellular and molecular biology, bioinformatics and molecular pharmacology.

In February 2020, he joined the Medicinal Chemistry and Synthesis (MCS) laboratory at The Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), where he obtained a Ramón y Cajal grant. In 2022, he passed a competitive examination to become a permanent researcher at the Spanish National Research Council (CSIC). His main research interest has been the activation dynamics of G protein-coupled receptors (GPCRs).

It is important to highlight that during these years he has established a network of collaborators that has played an essential role in the development of the emerging field known as photopharmacology. This emerging area of research is based on the development and use of light-controlled drugs to regulate proteins with high temporal and spatial precision in their native environment.

Current glaucoma treatments present significant limitations due to side effects, low efficacy, and poor patient adherence. Within the framework of GLAUxIS, we are developing visible light-activated drugs that allow for precise, safe, and localized control of intraocular pressure.
We propose an innovative strategy based on photopharmacology to address various therapeutic needs, including cardiovascular diseases. This approach would enable precise and reversible regulation of cardiac activity, with potential to temporarily improve its function and help stabilize rhythm disturbances in critical situations.